A neoclassical-style building constructed in the 17th century, which served as the headquarters of the Colegio de San Nicolás. 

Originally founded by Vasco de Quiroga in 1540 in Pátzcuaro, it was known as the Colegio de San Nicolás Obispo and later as the Colegio de San Nicolás de Hidalgo. This college was led by Rector Miguel Hidalgo, and outstanding student José María Morelos y Pavón. It became one of the most important educational institutions during the colonial era.

In 1810, with the start of the Independence movement, the colonial government closed the Colegio de San Nicolás, and it was used as a prison and military barracks. In 1845, the building was reconstructed, and after restoration, Governor Melchor Ocampo reopened the college with a secular character.

However, in 1863, during the French Intervention, it once again closed its doors. It wasn't until 1887 that the building was inaugurated in its current appearance, mostly following a neoclassical style. Shortly after, President Porfirio Díaz donated the monument to Miguel Hidalgo, which stands in the center of the main courtyard.

In 1930, the building was declared a National Monument, and in 1932, two murals were painted on the side walls of the second floor, both by artist Fermín Revueltas. Later, in 1934, the third mural was created by Marion Greenwood in the second-floor patio of the college.

There is a room named after Melchor Ocampo that houses his heart and some objects that belonged to him. Ocampo was a prominent politician and naturalist during the Reform era.

Currently, the building houses one of the high schools of the Universidad Michoacana.