Its construction dates back to 1694 when a chapel to the Virgin of Guadalupe was built at the request of Juan Alonso Martínez Peredo, a master blacksmith and firework maker. 

The temple was dedicated in 1722, and its facade showcases the innovative style of architect Diego de la Sierra, who imparted a unique character to Mexican Baroque. In 1765, the annexed school for the Mercedarians was built.

The entire front is decorated with tiles in horizontal zigzag stripes, and its bases are covered in brick, which also highlights tile panels.

The facade is elaborated in stone, in a sober baroque style with fluted pilasters. At the top, there is a balustrade that outlines the ensemble.

The towers feature Solomonic columns with abundant relief ornaments. 

Regarding the domes, they also incorporate a fusion of Talavera pottery and brick petatillo.

The interior is rather sober in a neoclassical style. Adjacent to it is the chapel dedicated to the Virgin of Sorrows.

Every December 12th, this sanctuary welcomes hundreds of pilgrims.