Its construction began in 1536 and is the oldest civil viceregal building in Mexico

The Regional Museum was built on the ruins of a place called Tlatlocayacalli, which was used to deliver tributes to the Tlahuica chieftain.

Throughout its history, it has had different uses, including being the residence of Hernán Cortés between 1531 and 1535 when he received the title of Marqués del Valle de Oaxaca in Spain.

Between 1747 and 1821, the Crown's prosecutors installed the Royal Prison of Cuernavaca in this building, where José María Morelos y Pavón was imprisoned. Later, it served as the headquarters of the Palace of the Republic, the Government Palace of the State, and currently houses the Regional Museum.

At the entrance, there are remains of a Tlahuica construction, as well as three monoliths, two of which come from Cuernavaca, while the third is a commemorative monument from the Aztecs known as "piedra de los encantos" (charms stone) or chimalli.

On the eastern side of the palace, you will find a viewpoint where Diego Rivera captured the history of Mexico in three murals called "La Historia de Morelos: Conquista y Revolución," consisting of eight panels measuring 150 meters. You can also admire murals by the Spanish painter Salvador Tarazona depicting the pre-Hispanic and revolutionary eras, which were created in 1938.

The museum has 20 rooms spread over two floors, showcasing the history of Morelos. The first level covers the pre-Hispanic period, while the second displays objects related to the conquest, colonial era, revolution, and contemporary times.

Within its exhibition, you'll find various monoliths and the clock machinery that was once in the Cathedral in the 16th century.

The museum has a bookstore, a shop, an auditorium, and guided tours.